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Rabbit Polyclonal Antibody to OPTN

CAT: 1725-P08650-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P08650-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins.
Product Name Alternative
NRP; FIP2; HIP7; HYPL; ALS12; GLC1E; TFIIIA-INTP
Swiss Prot
Q96CV9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein of human OPTN
Clonality
Polyclonal
Applications
IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
OPTN