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Rabbit Polyclonal Antibody to EID1

CAT: 1725-P08269-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P08269-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
E1A-like inhibitor of differentiation-1 (EID-1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID-1 also acetylates both histones and non-histone proteins such as NCOA3 co-activator. By acetylating histones, EID-1 gives a specific tag for transcriptional activation. In addition to binding Rb and p300, EID-1 also binds to phosphorylated CREB protein, mediating cAMP gene regulation. EID-1 augments the activity of phosphorylated CREB and activates transcription of cAMP responsive genes as a co-activator.
Product Name Alternative
CRI1; EID-1; RBP21; PTD014; C15orf3; PNAS-22; IRO45620
Swiss Prot
Q9Y6B2
Host
Rabbit
Reactivity
Human
Immunogen
Fusion protein of human EID1
Clonality
Polyclonal
Applications
IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
EID1