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Rabbit Polyclonal Antibody to BCAS2

CAT: 1725-P08063-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P08063-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BCAS2 (breast carcinoma amplified sequence 2), also designated DAM1 (DNA amplified in mammary carcinoma 1 protein) or spliceosome-associated SPF 27, is a ubiquitously expressed nuclear protein that was originally identified as being overexpressed in various breast cancer cell lines. BCAS2 is now known to be a component of the spliceosome, participating in the removal of introns from mRNA precursors. BCAS2 specifically interacts (in a ligand-independent manner) with TR∫ (thyroid hormone receptor beta), ERå (estrogen receptor alpha), ER∫, PR (progesterone receptor), and PPAR© (Peroxisome proliferator-activated receptor gamma) . BCAS2 functions as an ER coactivator and is capable of enhancing ER-mediated transcription. This suggests that BCAS2 is involved in the development of breast cancer.
Product Name Alternative
DAM1; SPF27; Snt309
Swiss Prot
O75934
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Fusion protein of human BCAS2
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
BCAS2
Bands Size
26 kDa

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NBP1-77124-0.025mgRabbit Polyclonal BCAS2 Antibody
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