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Rabbit Polyclonal Antibody to ASCC1

CAT: 1725-P08031-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P08031-01Size:50 µL
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Description
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF) . The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
Product Name Alternative
P50; CGI-18; ASC1p50
Swiss Prot
Q8N9N2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Fusion protein of human ASCC1
Clonality
Polyclonal
Applications
IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
ASCC1

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