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Rabbit Polyclonal Antibody to MAPK8

CAT: 1725-P07402-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P07402-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Product Name Alternative
JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2
Swiss Prot
P45983
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein of human MAPK8
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
MAPK8
Bands Size
48 kDa

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