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Rabbit Polyclonal Antibody to CDK5

CAT: 1725-P07182-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P07182-01Size:50 µL
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Description
This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants.
Product Name Alternative
LIS7; PSSALRE
Swiss Prot
Q00535
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein of human CDK5
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
CDK5
Bands Size
33 kDa