Products for Research Use Only
RegisterLogin

Rabbit Polyclonal Antibody to XAB2

CAT: 1725-P05985-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1725-P05985-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
HCNP, also known as XAB2 (Xeroderma pigmentosum group A (XPA) binding protein 2), HCRN, SYF1 or NTC90, is a nuclear protein that participates in transcription, transcription-coupled repair (TCR) and pre-mRNA splicing. It contains fifteen tetratricopeptide repeat motifs and associates with nucleotide excision repair machinery. More specifically, HCNP associates with Cockayne syndrome group A and B proteins (CSA and CSB), RNA Polymerase II (Pol II) and XPA in response to DNA damage and is believed to function in the TCR pathway. HCNP also functions as an essential component of a pre-mRNA splicing complex of the spliceosome (composed of AQR (aquarius), PRP19, CCDC16, HCNP, ISY1 and Cyclophilin E) and is required for proper RNA synthesis in the cell. In addition, HCNP functions as a component of the RAR corepressor complex with RARå and HDAC3 and exhibits an inhibitory effect on ATRA-induced cell differentiation. This suggests that HCNP may function as useful target in cancer therapy.
Product Name Alternative
HCNP; HCRN; SYF1; NTC90
Swiss Prot
Q9HCS7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human XAB2
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
XAB2
Bands Size
100 kDa

Related Products

CatalogName
P10333-01Rabbit Polyclonal Antibody to RAB3IP
P42971-01Rabbit Polyclonal Antibody to ECFP Rabbit
P42972-01Rabbit Polyclonal Antibody to EYFP Rabbit
P42358-01Rabbit Polyclonal Antibody to CDYLy2 Antibod
P13710-01Rabbit Polyclonal Antibody to CCAR2
P13706-01Rabbit Polyclonal Antibody to CEMIP
P13703-01Rabbit Polyclonal Antibody to PUM3
P13702-01Rabbit Polyclonal Antibody to KIR2DL5A
P13700-01Rabbit Polyclonal Antibody to KHK
P13690-01Rabbit Polyclonal Antibody to KCNN3

Alternative Products

CatalogName
NBP2-58367Rabbit Polyclonal XAB2 Antibody
TA369479XAB2 Rabbit Polyclonal Antibody
GTR18437021XAB2 Rabbit Polyclonal Antibody (BF555)
GTR18437019XAB2 Rabbit Polyclonal Antibody (BF647)
GTR18437016XAB2 Rabbit Polyclonal Antibody (PerCP)
GTR18369328XAB2 Rabbit Polyclonal Antibody (FITC)
GTR17829957XAB2 Rabbit Polyclonal Antibody (RBITC)
GTR17829526XAB2 Rabbit Polyclonal Antibody (Cy7)
GTR17774461XAB2 Rabbit Polyclonal Antibody (Cy5)
GTR18437025XAB2 Rabbit Polyclonal Antibody (BF350)

Popular Products