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Rabbit Polyclonal Antibody to CHD3

CAT: 1725-P05488-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P05488-01Size:50 µL
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Description
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Product Name Alternative
ZFH; Mi-2a; SNIBCPS; Mi2-ALPHA
Swiss Prot
Q12873
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human CHD3
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
CHD3
Bands Size
226 kDa