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Rabbit Polyclonal Antibody to TBC1D4

CAT: 1725-P05394-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P05394-01Size:50 µL
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Description
TBC1 domain family member 4 (TBC1D4), also designated AS160, can be insulin- and/or AKT1-induced. Insulin-stimulated phosphorylation is required for GLUT4 translocation. TBC1D4 may play a role as a GTPase activating protein for proteins in the Rab family. It is expressed primarily in skeletal muscle and heart, as well as spleen, lymph node and leukocytes. Defects in the TBC1D4 gene may cause atopic dermatitis (AD), sometimes referred to as eczema, an atopic chronic skin disease. The skin of affected individuals reacts to irritants or allergens and becomes red, flaky and itchy. The skin is also more vulnerable to inflammations, and symptoms can grow or disappear over time.
Product Name Alternative
AS160
Swiss Prot
O60343
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human TBC1D4
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
TBC1D4
Bands Size
147 kDa