Products for Research Use Only
RegisterLogin

Rabbit Polyclonal Antibody to SRGAP1

CAT: 1725-P05359-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1725-P05359-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SRGAP1 contains an FCH (Fes/CIP4 homology) domain, a Rho-GAP domain and an SH3 domain. In the presence of Slit, SRGAP1 (via its SH3 domain) binds to the CC3 motif in robo (a protein responsible for mediating the repulsive effect of Slit) with higher affinity and inhibits Cdc42 activity in a robo/SRGAP-dependent manner. More specifically, SRGAP1 increases the intrinsic GTPase activity of Cdc42, thereby converting it to its inactive, GDP-bound form. Inactivation of Cdc42 ultimately leads to a decrease in actin polymerization.
Product Name Alternative
ARHGAP13
Swiss Prot
Q7Z6B7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human SRGAP1
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
SRGAP1
Bands Size
124 kDa

Related Products

CatalogName
P08804-01Rabbit Polyclonal Antibody to SRGAP3
P33293-01Rabbit Polyclonal Antibody to SRGAP2
P33334-01Rabbit Polyclonal Antibody to SRGAP3
P12242-01Rabbit Polyclonal Antibody to SRGAP2
P10333-01Rabbit Polyclonal Antibody to RAB3IP
P42971-01Rabbit Polyclonal Antibody to ECFP Rabbit
P42972-01Rabbit Polyclonal Antibody to EYFP Rabbit
P42358-01Rabbit Polyclonal Antibody to CDYLy2 Antibod
P13710-01Rabbit Polyclonal Antibody to CCAR2
P13706-01Rabbit Polyclonal Antibody to CEMIP

Alternative Products

CatalogName
GTR18037849-01SRGAP1 Rabbit Polyclonal Antibody
NB100-60650Rabbit Polyclonal SRGAP1 Antibody
GTR18513405SRGAP1 Rabbit Polyclonal Antibody (BF647)
GTR18513404SRGAP1 Rabbit Polyclonal Antibody (BF680)
GTR17822781SRGAP1 Rabbit Polyclonal Antibody (AP)
GTR18360224Srgap1 Rabbit Polyclonal Antibody (FITC)
GTR17765218SRGAP1 Rabbit Polyclonal Antibody (Biotin)
GTR17765219SRGAP1 Rabbit Polyclonal Antibody (HRP)
GTR18513407SRGAP1 Rabbit Polyclonal Antibody (BF555)
GTR18513406SRGAP1 Rabbit Polyclonal Antibody (BF594)

Popular Products