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Rabbit Polyclonal Antibody to PYCARD

CAT: 1725-P03663-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P03663-01Size:50 µL
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Description
This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD) . The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.
Product Name Alternative
ASC; TMS; TMS1; CARD5; TMS-1
Swiss Prot
Q9ULZ3
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Fusion protein of human PYCARD
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
PYCARD
Bands Size
22 kDa

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