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Rabbit Polyclonal Antibody to TMPRSS2

CAT: 1725-P01672-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P01672-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. This protein also facilitates entry of viruses into host cells by proteolytically cleaving and activating viral envelope glycoproteins. Viruses found to use this protein for cell entry include Influenza virus and the human coronaviruses HCoV-229E, MERS-CoV, SARS-CoV and SARS-CoV-2 (COVID-19 virus) . Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product Name Alternative
PRSS10
Swiss Prot
O15393
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Fusion protein of human TMPRSS2
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
TMPRSS2
Bands Size
54 kDa

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