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Rabbit Polyclonal Antibody to PRKAR2A

CAT: 1725-P01647-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P01647-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER) .
Product Name Alternative
PKR2; PRKAR2
Swiss Prot
P13861
Host
Rabbit
Reactivity
Human
Immunogen
Fusion protein of human PRKAR2A
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
PRKAR2A
Bands Size
46 kDa

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