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Rabbit Polyclonal Antibody to BCCIP

CAT: 1725-P01122-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P01122-01Size:50 µL
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Description
This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.
Product Name Alternative
TOK1; TOK-1
Swiss Prot
Q9P287
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Fusion protein of human BCCIP
Clonality
Polyclonal
Applications
WB
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
BCCIP
Bands Size
36 kDa