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Rabbit Polyclonal Antibody to CARF

CAT: 1725-P00910-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P00910-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CARF (calcium-response factor), also known as ALS2CR8 (amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein) or NYD-SP24, is a 725 amino acid nuclear protein. Expressed in a wide variety of tissues with highest expression in the hippocampus, CARF is thought to be a transcription factor that associates with the p53 tumor suppression pathway. CARF cooperates, co-localizes and is co-regulated with ARF, an ADP-ribosylation factor, and, through this interaction, helps to mediate ARF-p53-induced apoptotic signaling. This apoptotic pathway is implicated in cell cycle control, proper cellular development, response to DNA damage and the aging process, suggesting that CARF participates in various events throughout the cell.
Product Name Alternative
ALS2CR8; NYD-SP24
Swiss Prot
Q8N187
Host
Rabbit
Reactivity
Human
Immunogen
Fusion protein of human CARF
Clonality
Polyclonal
Applications
WB
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
CARF
Bands Size
81 kDa

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