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Rabbit Polyclonal Antibody to PAK4

CAT: 1725-P00602-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P00602-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Swiss Prot
O96013
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Fusion protein of human PAK4
Clonality
Polyclonal
Applications
IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
PAK4