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DAPTA

CAT: 0804-HY-P1034-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-P1034-01Size:5 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DAPTA is a synthetic peptide, functions as a viral entry inhibitor by targeting selectively CCR5, and shows potent anti-HIV activities.
CAS Number
[106362-34-9]
Product Name Alternative
D-Ala-peptide T-amide; Adaptavir
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
CCR; HIV
Type
Peptides
Related Pathways
Anti-infection; GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Infection; Endocrinology
Assay Protocol
https://www.medchemexpress.com/DAPTA.html
Purity
98.87
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=C(C[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](C)N)=O)CO)=O)[C@@H](C)O)=O)[C@@H](C)O)=O)[C@@H](C)O)=O)CC(N)=O)=O)C(N[C@@H]([C@@H](C)O)C(N)=O)=O)C=C1
Molecular Formula
C35H56N10O15
Molecular Weight
856.88
Precautions
H302, H315, H319, H335
References & Citations
[1]Pollicita M, et al. Profound anti-HIV-1 activity of DAPTA in monocytes/macrophages and inhibition of CCR5-mediated apoptosis in neuronal cells. Antivir Chem Chemother. 2007;18 (5) :285-95.|[2]Polianova MT, et al. Chemokine receptor-5 (CCR5) is a receptor for the HIV entry inhibitor peptide T (DAPTA) . Antiviral Res. 2005 Aug;67 (2) :83-92.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
Phase 2
Isoform
CCR5; HIV-1

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