(R)-JNJ-40418677
CAT:
804-HY-100604A-04
Size:
25 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
(R)-JNJ-40418677
- CAS Number: 1146594-85-5
- UNSPSC Description: (R)-JNJ-40418677 is the R-enantiomer of JNJ-40418677 (HY-100604)[1].
- Target Antigen: Amyloid-β; γ-secretase
- Type: Reference compound
- Related Pathways: Neuronal Signaling;Stem Cell/Wnt
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/r-jnj-40418677.html
- Purity: 99.27
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: CC(C)C[C@H](C1=CC(C2=CC=C(C=C2)C(F)(F)F)=CC(C3=CC=C(C=C3)C(F)(F)F)=C1)C(O)=O
- Molecular Weight: 480.44
- References & Citations: [1]Van Broeck B, et al. Chronic treatment with a novel γ-secretase modulator, JNJ-40418677, inhibits amyloid plaque formation in a mouse model of Alzheimer's disease. Br J Pharmacol. 2011 May;163(2):375-89.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported