JNJ-40418677

• Target:

  Others|||Gamma-secretase|||Beta Amyloid

• Related Pathways:

  Others|||Neuroscience|||Proteases/Proteasome|||Stem Cells

• Bioactivity:

  JNJ-40418677 is a ?-secretase modulator that selectively blocks ?-site cleavage of the APP without affecting the processing of Notch.

• Smiles:

  CC(C)C[C@H](C(O)=O)c1cc(cc(c1)-c1ccc(cc1)C(F)(F)F)-c1ccc(cc1)C(F)(F)F

• Molecular Formula:

  C26H22F6O2

• Molecular Weight:

  480.44

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1146594-87-7