Calcium dextrofolinate

• UNSPSC Description:

  Calcium dextrofolinate is a stereoisomer of Calcium folinate. Calcium folinate (Folinic acid calcium) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/calcium-dextrofolinate.html

• Smiles:

  O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(NC[C@H]2N(C=O)C3=C(N=C(N)NC3=O)NC2)C=C1)=O.[Ca]

• Molecular Weight:

  513.52

• References & Citations:

  [1]Shui-Jie Shen, et al. [Direct resolution of calcium folinate stereoisomers using a bovine serum albumin chiral HPLC column]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2004 Jan;33(1):11-4.|[2]Keshava C, et al. Inhibition of methotrexate-induced chromosomal damage by folinic acid in V79 cells. Mutat Res. 1998 Feb 2;397(2):221-8.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  115940-48-2