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Calcium dextrofolinate

CAT: 0804-HY-115429-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-115429-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Calcium dextrofolinate is a stereoisomer of Calcium folinate. Calcium folinate (Folinic acid calcium) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity[1].
CAS Number
115940-48-2
Product Name Alternative
(6R) -Leucovorin (calcium) ; (6R) -Folinic acid (calcium)
UNSPSC
12352005
Target
Drug Derivative
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/calcium-dextrofolinate.html
Purity
95.33
Solubility
H2O : 1.96 mg/mL (ultrasonic; warming; adjust pH to 2 with 1 M HCL; heat to 60°C)
Smiles
O=C([O-])CC[C@@H](C([O-])=O)NC(C1=CC=C(NC[C@H]2N(C=O)C3=C(N=C(N)NC3=O)NC2)C=C1)=O.[Ca+2]
Molecular Formula
C20H21CaN7O7
Molecular Weight
511.50
References & Citations
[1]Shui-Jie Shen, et al. [Direct resolution of calcium folinate stereoisomers using a bovine serum albumin chiral HPLC column]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2004 Jan;33 (1) :11-4.|[2]Keshava C, et al. Inhibition of methotrexate-induced chromosomal damage by folinic acid in V79 cells. Mutat Res. 1998 Feb 2;397 (2) :221-8.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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