Thalidomide-4-O-C4-NH2 (hydrochloride)
CAT:
804-HY-130948B-01
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Thalidomide-4-O-C4-NH2 (hydrochloride)
- CAS Number: 2376990-29-1
- UNSPSC Description: Thalidomide-4-O-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide (HY-14658) based cereblon ligand and a linker used in PROTAC technology.
- Target Antigen: Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
- Type: Reference compound
- Related Pathways: Apoptosis;Autophagy;PROTAC
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/thalidomide-4-o-c4-nh2-hydrochloride.html
- Purity: 99.35
- Solubility: DMSO : 50 mg/mL (ultrasonic)
- Smiles: O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3OCCCCN)=O.[H]Cl
- Molecular Weight: 381.81
- References & Citations: [1]Fischer ES, et al. Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide. Nature. 2014 Aug 7;512(7512):49-53. [Content Brief]
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported