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Debutyldronedarone-d7

CAT: 0804-HY-12753S-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-12753S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Debutyldronedarone-d7 is deuterium labeled Debutyldronedarone. Debutyldronedarone is a major circulating active metabolite of dronedarone in humans.Debutyldronedarone exhibits a potency that is 1/10 to 1/3 of that of the parent agent[1][2].
Product Name Alternative
SR35021-d7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Purity
98.0
Solubility
10 mM in DMSO
Smiles
CS(=O)(NC1=CC=C(OC(CCCC)=C2C(C3=CC=C(OCCCNCC([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])C=C3)=O)C2=C1)=O
Molecular Formula
C27H29D7N2O5S
Molecular Weight
507.69
Precautions
H302, H315, H319, H335
References & Citations
[1]Cen Xie, et al. Simultaneous determination of dronedarone and its active metabolite debutyldronedarone in human plasma by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study.J Chromatogr B Analyt Technol Biomed Life Sci|[2]Marina Santos, et al.Synthesis and characterization of new related substances of the antiarrhythmic drug dronedarone hydrochloride. J Pharm Biomed Anal. 2015 Oct 10;114:441-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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