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Toripristone

CAT: 0804-HY-19814Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-19814Size:1 Each
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Description
Toripristone (RU-40555) is a cortisol receptor inhibitor. Toripristone combined with clarithromycin can increase the antibacterial activity of Mycobacterium avium complex infection[1].
CAS Number
91935-26-1
Product Name Alternative
RU-40555
UNSPSC
12352005
Target
Glucocorticoid Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/toripristone.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@](CC[C@@]2(O)C#CC)([H])[C@@]3([H])C([C@@H](C4=CC=C(C=C4)N(C)C(C)C)C1)=C5C(CC3)=CC(CC5)=O
Molecular Formula
C31H39NO2
Molecular Weight
457.65
References & Citations
[1] Lazard T, et al. Efficacy of granulocyte colony-stimulating factor and RU-40555 in combination with clarithromycin against Mycobacterium avium complex infection in C57BL/6 mice. Antimicrob Agents Chemother. 1993 Apr;37 (4) :692-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T88330-01Toripristone

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