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Rocbrutinib

CAT: 0804-HY-156640-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-156640-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rocbrutinib is a Bruton's tyrosine kinase inhibitor with antineoplastic effect[1].
CAS Number
2485861-07-0
Product Name Alternative
LP-168
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rocbrutinib.html
Purity
99.76
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C1C2=CC(CC(C)(C3)C)=C3N2CCN1C4=C(C(C(N=C5NC6=CC(NC(C=C)=O)=C(N7[C@H](CN(C8CCOCC8)CC7)C)C=C6)=CN(C)C5=O)=CC=N4)CO
Molecular Formula
C42H51N9O5
Molecular Weight
761.91
References & Citations
[1]Chen Yi, et al. Preparation of pyrrolopyrazines and related heterocycles as inhibitors of BTK and mutants thereof for the treatment of neoplastic, autoimmune and inflammatory disorders. World Intellectual Property Organization, WO2020176403 A1 2020-09-03.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

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CatalogName
GTR19219219-01Rocbrutinib

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