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Ɑ-Methoxy-ω-Succinamic Acid NHS Ester PEG

CAT: 0927-12750-35.5GSize: 5 gDry Ice: NoHazardous: No
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CAT#:0927-12750-35.5GSize:5 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PEG-NHS ester derivatives are active esters and useful reagents to pegylate proteines, peptides or any other surfaces with a free primary amino group to form stable amide bonds. The Reaction requires a neutral to alkaline pH (7 to 8.5) to proceed. However, hydrolysis competes with aminolysis of the active ester and also increases with higher pH. Thus, working with excess PEG-NHS is necessary to obtain high pegylation yields. The amido succinic acid NHS ester derivative has a C4 amide linkage between PEG and the NHS ester group. It is a comparably reactive PEG active ester with a hydrolysis half-life of a few minutes at pH 8.
Specifications
750 Dalton

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