OVA (250-264)

• Target:

  MHC

• Related Pathways:

  Immunology/Inflammation

• Bioactivity:

  OVA (250-264) (OVAvac) (OVAp) is an antigenic peptide derived from chicken egg ovalbumin, presented by class I MHC molecule H-2Kb. This peptide, when combined with ?MSLN (anti-MSLN antibody), significantly stimulates the production and infiltration of antigen-specific CD8+ T cells, thereby enhancing antitumor effects in an in situ pancreatic cancer mouse model. It is applicable in developing tumor neoantigen vaccines for pancreatic cancer immunotherapy research.

• Smiles:

  [C@H](CC1=CC=CC=C1)(C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CCCCN)=O)CCC(O)=O)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CO)N)=O)=O)CC(C)C)=O)CCC(O)=O)=O)CCC(N)=O)=O)CC(C)C)=O)CCC(O)=O)=O)CO)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CC(N)=O)=O

• Molecular Formula:

  C77H126N18O26

• Molecular Weight:

  1719.93

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  355012-70-3