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P9R

CAT: 0931-TP3824-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP3824-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2484874-12-4
Target
SARS-CoV, Influenza Virus, Virus Protease
Related Pathways
Microbiology/Virology
Bioactivity
P9R is an antiviral peptide with broad-spectrum activity against coronaviruses (SARS-CoV-2, MERS-CoV, and SARS-CoV), influenza A H1N1 virus (A (H1N1) pdm09), influenza A H7N9 virus (A (H7N9) virus), and rhinovirus. It binds directly to viruses and inhibits virus-host endosomal acidification. P9R significantly protects mice from infection by influenza A H1N1 virus (A (H1N1) pdm09) without leading to resistant viruses. P9R is applicable in studying pH-dependent respiratory viruses.
Smiles
C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC(N)=O)N)=O)=O)C)=O)[C@H](CC)C)=O)CS)=O)C(NCC(=O)N1[C@H](C(N[C@H](C(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O)CS)=O)CS)=O)CCCNC(=N)N)=O)C(C)C)=O)CCCNC(=N)N)=O)=O)CCCNC(=N)N)=O)=O)CS)=O)CC(N)=O)=O)=O)[C@H](CC)C)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)=O)C)=O)[C@@H](C)O)=O)CCC2)CS)=O)CCC1)=O)C=5C=6C(NC5)=CC=CC6
Molecular Formula
C144H232N52O35S5
Molecular Weight
3412.03
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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