YVPGP

CAT: 0931-TP3769-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-TP3769-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2095286-57-8

Target

PI3K, Apoptosis, Caspase, Akt, Bcl-2 Family, mTOR

Related Pathways

Proteases/Proteasome, PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, Apoptosis

Bioactivity

YVPGP is an oligopeptide extracted from Anthopleura anjunae. It exhibits significant anti-tumor activity by mediating the PI3K/AKT/mTOR signaling pathway. YVPGP can arrest DU-145 cells in the S phase and induce apoptosis (apoptosis) through mitochondrial and death receptor pathways (caspase3, 7, 8, 9) . It effectively inhibits tumor growth in a DU-145 xenograft mouse model, showing potential for prostate cancer research.

Smiles

C([C@@H](NC([C@H](CC1=CC=C(O)C=C1)N)=O)[C@H](C)C)(=O)N2[C@H](C(NCC(=O)N3[C@H](C(O)=O)CCC3)=O)CCC2

Molecular Formula

C26H37N5O7

Molecular Weight

531.6

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Yvpgp

CAS Number	2095286-57-8
PubChem CID	177746410
IUPAC Name	(2S)-1-[2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carboxylic acid
Molecular Formula	C26H37N5O7
Molecular Weight	531.6
XLogP	-2
Topological Polar Surface Area	182
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	10
Heavy Atom Count	38
Formal Charge	0
Complexity	889

SMILES

CC(C)[C@@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)N2CCC[C@H]2C(=O)O)NC(=O)[C@H](CC3=CC=C(C=C3)O)N

InChI

InChI=1S/C26H37N5O7/c1-15(2)22(29-23(34)18(27)13-16-7-9-17(32)10-8-16)25(36)31-12-3-5-19(31)24(35)28-14-21(33)30-11-4-6-20(30)26(37)38/h7-10,15,18-20,22,32H,3-6,11-14,27H2,1-2H3,(H,28,35)(H,29,34)(H,37,38)/t18-,19-,20-,22-/m0/s1

InChIKey

ODXFAMVHVQBPTQ-XWUOBKMESA-N

Chemical Structure

2D Structure

CAS: 2095286-57-8

CID: 177746410

Formula: C26H37N5O7

MW: 531.6

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	531.6
XLogP3	-2
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	10
Exact Mass	531.26929854
Monoisotopic Mass	531.26929854
Topological Polar Surface Area	182 Å²
Heavy Atom Count	38
Formal Charge	0
Complexity	889
Isotope Atom Count	0
Defined Atom Stereocenter Count	4
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
HY-P10992	YVPGP

YVPGP

Chemical Information

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