KT2

• Target:

  Antibacterial|||Antibiotic

• Related Pathways:

  Microbiology/Virology

• Bioactivity:

  KT2 is a cationic amphipathic antimicrobial peptide. It is capable of completely killing (E. coli) O157:H7 cells. KT2 exhibits strong antibiofilm activity, preventing the formation of E. coli O157:H7 biofilms. Additionally, KT2 effectively binds to LPS on bacterial surfaces, interacts with the lipids in liposomes, and displays high permeability, allowing it to penetrate bacterial cells and bind with DNA and other cytoplasmic membranes.

• Smiles:

  C ([C@@H] (C (N[C@@H] (CC=1C=2C (NC1) =CC=CC2) C (N[C@H] (C (N[C@H] (C (N[C@@H] (CC=3C=4C (NC3) =CC=CC4) C (N[C@@H] (CC=5C=6C (NC5) =CC=CC6) C (N) =O) =O) =O) CCCCN) =O) CCCCN) =O) =O) NC ([C@@H] (NC ([C@H] (CC=7C=8C (NC7) =CC=CC8) NC ([C@H] (CC=9C=%10C (NC9) =CC=CC%10) NC ([C@@H] (NC ([C@H] (CC%11=CC=C (O) C=C%11) NC ([C@@H] (NC (=O) [C@H]%12N (C ([C@@H] (NC ([C@@H] (NC (CNC ([C@H] (CC (N) =O) N) =O) =O) C (C) C) =O) CCC (N) =O) =O) CCC%12) CCCCN) =O) =O) CCCCN) =O) =O) =O) CCCCN) =O) C=%13C=%14C (NC%13) =CC=CC%14

• Molecular Formula:

  C126H165N31O20

• Molecular Weight:

  2433.85

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1539295-32-3