KT2

CAT: 0931-TP3763-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-TP3763-01Size:10 mg
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CAS Number
1539295-32-3
Target
Antibacterial|||Antibiotic
Related Pathways
Microbiology/Virology
Bioactivity
KT2 is a cationic amphipathic antimicrobial peptide. It is capable of completely killing (E. coli) O157:H7 cells. KT2 exhibits strong antibiofilm activity, preventing the formation of E. coli O157:H7 biofilms. Additionally, KT2 effectively binds to LPS on bacterial surfaces, interacts with the lipids in liposomes, and displays high permeability, allowing it to penetrate bacterial cells and bind with DNA and other cytoplasmic membranes.
Smiles
C([C@@H](C(N[C@@H](CC=1C=2C(NC1)=CC=CC2)C(N[C@H](C(N[C@H](C(N[C@@H](CC=3C=4C(NC3)=CC=CC4)C(N[C@@H](CC=5C=6C(NC5)=CC=CC6)C(N)=O)=O)=O)CCCCN)=O)CCCCN)=O)=O)NC([C@@H](NC([C@H](CC=7C=8C(NC7)=CC=CC8)NC([C@H](CC=9C=%10C(NC9)=CC=CC%10)NC([C@@H](NC([C@H](CC%11=CC=C(O)C=C%11)NC([C@@H](NC(=O)[C@H]%12N(C([C@@H](NC([C@@H](NC(CNC([C@H](CC(N)=O)N)=O)=O)C(C)C)=O)CCC(N)=O)=O)CCC%12)CCCCN)=O)=O)CCCCN)=O)=O)=O)CCCCN)=O)C=%13C=%14C(NC%13)=CC=CC%14
Molecular Formula
C126H165N31O20
Molecular Weight
2433.85
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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