Products for Research Use Only

(123B9) 2-Motif

CAT: 0931-TP3741-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP3741-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Ephrin Receptor
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
(123B9) 2-Motif is a selective agonist of the EphA2 receptor with a dissociation constant (Kd) of 4.9 μM and does not bind to EphA4. It functions by inducing phosphorylation and oligomerization of the EphA2 receptor, promoting receptor activation and internalization. (123B9) 2-Motif is primarily used in research on targeted drug delivery for cancers overexpressing EphA2, such as breast cancer, to reduce circulating tumor cells and inhibit metastasis.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C