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RT2

CAT: 0931-TP3706-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP3706-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1539295-33-4
Target
Antibacterial
Related Pathways
Microbiology/Virology
Bioactivity
RT2 is a cationic amphiphilic antimicrobial peptide rich in tryptophan that primarily targets lipopolysaccharides (LPS) on bacterial surfaces and intracellular DNA. By binding to surface LPS, RT2 interacts with cytoplasmic membrane phospholipids, enabling rapid penetration of the bacterial cell membrane and subsequent binding to cytoplasmic components such as DNA, exerting its antibacterial effects. RT2 holds potential for research into acute and chronic infections caused by planktonic bacteria.
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C([C@@H](C(N[C@@H](CC=1C=2C(NC1)=CC=CC2)C(N[C@H](C(N[C@H](C(N[C@@H](CC=3C=4C(NC3)=CC=CC4)C(N[C@@H](CC=5C=6C(NC5)=CC=CC6)C(N)=O)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)NC([C@@H](NC([C@H](CC=7C=8C(NC7)=CC=CC8)NC([C@H](CC=9C=%10C(NC9)=CC=CC%10)NC([C@@H](NC([C@H](CC%11=CC=C(O)C=C%11)NC([C@@H](NC(=O)[C@H]%12N(C([C@@H](NC([C@@H](NC(CNC([C@H](CC(N)=O)N)=O)=O)C(C)C)=O)CCC(N)=O)=O)CCC%12)CCCCN)=O)=O)CCCNC(=N)N)=O)=O)=O)CCCNC(=N)N)=O)C=%13C=%14C(NC%13)=CC=CC%14
Molecular Formula
C126H165N39O20
Molecular Weight
2545.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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