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Amilo-5MER

CAT: 0931-TP3229-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP3229-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1860001-61-1
Target
Beta Amyloid, Interleukin
Related Pathways
Neuroscience, Immunology/Inflammation
Bioactivity
Amilo-5MER (5-MP) is an orally active and selective inhibitor of serum amyloid A (SAA) . It specifically suppresses the release of pro-inflammatory cytokines IL-6 and IL-1β in SAA-activated cells. Amilo-5MER reduces chronic inflammation and alleviates symptoms of diseases such as rheumatoid arthritis (RA), inflammatory bowel disease (IBD), and multiple sclerosis (MS) . It holds potential for research in autoimmune and chronic inflammatory diseases.
Smiles
[C@H](C(N[C@@H](C(C)C)C(N)=O)=O)(NC([C@@H](NC([C@@H](NC([C@H](CCSC)NC(C)=O)=O)[C@@H](C)O)=O)C)=O)CC(O)=O
Molecular Formula
C23H40N6O9S
Molecular Weight
576.664
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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