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GeX-2

CAT: 0931-TP3132-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP3132-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2900996-95-2
Target
AChR, GABA Receptor, Calcium Channel
Related Pathways
Neuroscience, Metabolism, Membrane transporter/Ion channel
Bioactivity
GeX-2 is a truncated analogue of αO-conotoxin. It has the ability to activate GABAB receptors and inhibit α9α10nAChR as well as CaV2.2 channels. Additionally, GeX-2 is effective in alleviating pain in a rat model of chronic constriction injury.
Smiles
C(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(O)=O)C(N)=O)=O)[C@@H](C)O)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CC(O)=O)=O)(=O)[C@H]3N(C([C@@H](NC([C@@H](NC([C@H](CC4=CC=C(O)C=C4)NC([C@H](CCCNC(=N)N)NC(CN)=O)=O)=O)CCCNC(=N)N)=O)CO)=O)CCC3
Molecular Formula
C103H169N43O27
Molecular Weight
2441.72
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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