GeX-2

• Target :

  AChR|||GABA Receptor|||Calcium Channel

• Related Pathways :

  Neuroscience|||Metabolism|||Membrane transporter/Ion channel

• Bioactivity :

  GeX-2 is a truncated analogue of ?O-conotoxin. It has the ability to activate GABAB receptors and inhibit ?9?10nAChR as well as CaV2.2 channels. Additionally, GeX-2 is effective in alleviating pain in a rat model of chronic constriction injury.

• Smiles :

  C(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(O)=O)C(N)=O)=O)[C@@H](C)O)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CC(O)=O)=O)(=O)[C@H]3N(C([C@@H](NC([C@@H](NC([C@H](CC4=CC=C(O)C=C4)NC([C@H](CCCNC(=N)N)NC(CN)=O)=O)=O)CCCNC(=N)N)=O)CO)=O)CCC3

• Molecular Formula :

  C103H169N43O27

• Molecular Weight :

  2441.72

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2900996-95-2