Ac-MRGDH-NH2

CAT: 0931-TP3057-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-TP3057-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

Integrin

Related Pathways

Cytoskeletal Signaling

Bioactivity

Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru (Ph2phen) 2 (κS, κN- (Ac-MRGDH-NH2) ) ]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru (Ph2phen) 2 (OH2) 2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.

Smiles

CC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N

Molecular Formula

C25H41N11O8S

Molecular Weight

655.727

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
HY-P10667	Ac-MRGDH-NH2
E-1105.0025	Ac-Leu-NH2
E-1160.0001	Ac-Phe-NH2
E-1140.0005	Ac-Met-NH2
E-2800.0001	Ac-Arg-NH2
E-1085.0005	Ac-Ile-NH2
E-1185.0005	Ac-Pro-NH2
E-1270.0005	Ac-Val-NH2
E-1225.0025	Ac-Trp-NH2
E-1010.0025	Ac-Ala-NH2

Ac-MRGDH-NH2

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