Products for Research Use Only
RegisterLogin

BIMAX2

CAT: 0931-TP2819-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-TP2819-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1105053-46-0
Bioactivity
BIMAX2 is a high-affinity peptide for nuclear localization signals (NLS) . It mimics the activity of classical nuclear localization signals (cNLS) by competitively binding to importin α, thereby inhibiting the interaction between cNLS-cargo proteins and importin α. BIMAX2 is utilized in studies to investigate the role of RBBP4 in regulating nuclear import efficiency and cellular senescence.
Smiles
C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCNC(=N)N)=O)CCC(O)=O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N1[C@H](C(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(O)=O)C(O)=O)=O)CC(C)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCC2)CCC1)CC(O)=O)=O)CC(O)=O)=O)CC(O)=O)=O)CC(O)=O)=O)CC(O)=O)=O)C=3C=4C(NC3)=CC=CC4
Molecular Formula
C146H254N64O41
Molecular Weight
3561.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Bimax2
CAS Number1105053-46-0
PubChem CID171989717
IUPAC Name(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-1-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]hexanoyl]amino]-5-carbamimidamidopentanoyl]amino]hexanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-carboxybutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-carboxypropanoyl]amino]-3-carboxypropanoyl]amino]-3-carboxypropanoyl]amino]-3-carboxypropanoyl]amino]-3-carboxypropanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]hexanoyl]amino]hexanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylpentanoyl]amino]butanedioic acid
Molecular FormulaC146H254N64O41
Molecular Weight3562.0
XLogP-30.5
Topological Polar Surface Area1840
Hydrogen Bond Donor Count70
Hydrogen Bond Acceptor Count57
Rotatable Bond Count139
Heavy Atom Count251
Formal Charge0
Complexity8410
SMILES
CC(C)C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]2CCCN2C(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)N
InChI
InChI=1S/C146H254N64O41/c1-73(2)64-93(126(241)208-100(135(250)251)71-109(223)224)201-124(239)91(42-23-61-184-146(172)173)198-122(237)89(40-21-59-182-144(168)169)197-118(233)85(36-17-55-178-140(160)161)191-111(226)78(29-5-9-47-147)187-114(229)81(32-8-12-50-150)200-132(247)101-43-24-62-209(101)134(249)102-44-25-63-210(102)133(248)99(70-108(221)222)207-131(246)98(69-107(219)220)206-130(245)97(68-106(217)218)205-129(244)96(67-105(215)216)204-128(243)95(66-104(213)214)203-127(242)94(65-74-72-185-77-28-4-3-26-75(74)77)202-125(240)92(45-46-103(211)212)199-123(238)90(41-22-60-183-145(170)171)192-113(228)80(31-7-11-49-149)188-116(231)83(34-15-53-176-138(156)157)190-112(227)79(30-6-10-48-148)189-117(232)84(35-16-54-177-139(158)159)194-120(235)87(38-19-57-180-142(164)165)196-121(236)88(39-20-58-181-143(166)167)195-119(234)86(37-18-56-179-141(162)163)193-115(230)82(33-14-52-175-137(154)155)186-110(225)76(151)27-13-51-174-136(152)153/h3-4,26,28,72-73,76,78-102,185H,5-25,27,29-71,147-151H2,1-2H3,(H,186,225)(H,187,229)(H,188,231)(H,189,232)(H,190,227)(H,191,226)(H,192,228)(H,193,230)(H,194,235)(H,195,234)(H,196,236)(H,197,233)(H,198,237)(H,199,238)(H,200,247)(H,201,239)(H,202,240)(H,203,242)(H,204,243)(H,205,244)(H,206,245)(H,207,246)(H,208,241)(H,211,212)(H,213,214)(H,215,216)(H,217,218)(H,219,220)(H,221,222)(H,223,224)(H,250,251)(H4,152,153,174)(H4,154,155,175)(H4,156,157,176)(H4,158,159,177)(H4,160,161,178)(H4,162,163,179)(H4,164,165,180)(H4,166,167,181)(H4,168,169,182)(H4,170,171,183)(H4,172,173,184)/t76-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-/m0/s1
InChIKey
WICQXNFILVTKRP-UIWUKXANSA-N
Chemical Structure
2D Structure
2D structure of Bimax2
CAS: 1105053-46-0
CID: 171989717
Formula: C146H254N64O41
MW: 3562.0
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight3562.0
XLogP3-30.5
Hydrogen Bond Donor Count70
Hydrogen Bond Acceptor Count57
Rotatable Bond Count139
Exact Mass3560.9791486
Monoisotopic Mass3559.9757938
Topological Polar Surface Area1840 Ų
Heavy Atom Count251
Formal Charge0
Complexity8410
Isotope Atom Count0
Defined Atom Stereocenter Count26
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
TP2829-01BIMAX1
TP2883-01BIMAX1 acetate
T84556-01Bima SA

Alternative Products

CatalogName
HY-P10600BIMAX2
HY-P10600A-01BIMAX2 (acetate)
GTR19065907-01BIMAX2 acetate

Popular Products