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α-Dendrotoxin

CAT: 0931-TP2759-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP2759-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
74504-53-3
Target
Sodium Channel, Potassium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
α-Dendrotoxin (α-DTX) is a small molecular peptide neurotoxin isolated from the venom of the African green mamba snake (Dendroaspis angusticeps) . This compound acts as a blocker for KV1.1, KV1.2, KV1.6, and ASIC channels. By inhibiting potassium channels, α-Dendrotoxin reduces the threshold for neuronal action potentials and increases the frequency of these potentials, thereby enhancing neuronal excitability. It is utilized in neurotoxicological research.
Molecular Formula
C305H478N98O84S6
Molecular Weight
7072
Shipping Conditions
Ice Packs
Storage Temperature
-20°C