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Sarafotoxin S6d

CAT: 0931-TP2726-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP2726-01Size:10 mg
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CAS Number
1446991-36-1
Target
Calcium Channel
Related Pathways
Membrane transporter/Ion channel, Metabolism
Bioactivity
Sarafotoxin S6d (STX-b) is a peptide toxin isolated from the venom of the Israeli burrowing asp. It induces various Electrocardiogram (ECG) changes such as myocardial ischemia and hyperkalemia. In rat aortas, Sarafotoxin S6d causes intense vasoconstriction dependent on extracellular calcium ions and exhibits positive inotropic effects in rat atria. This compound is useful for research into cardiovascular diseases.
Smiles
C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CN=CN1)NC(=O)[C@H]2NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC4=CC=C(O)C=C4)NC(=O)[C@H](CC(C)C)NC(=O)[C@]5(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@](NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@@H](N)CSSC2)[H])(CSSC5)[H])[H])[H])=O)CCC(N)=O)=O)CC(O)=O)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)C(O)=O)C=6C=7C(NC6)=CC=CC7
Molecular Formula
C112H163N27O34S5
Molecular Weight
2591.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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