Multi-Leu peptide

• Target :

  Autophagy

• Related Pathways :

  Autophagy

• Bioactivity :

  Multi-Leu peptide (ML-peptide), with a K i value of 22 nM, acts as a potent inhibitor of PACE4 by competitively binding to its active site and mimicking its substrate sequence, thus suppressing the enzyme's catalytic function. This compound is useful for investigating PACE4's specific role in the progression of prostate cancer.

• Smiles :

  [C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(C)C)NC(C)=O)=O)CC(C)C)=O)CC(C)C)=O)CC(C)C)=O)(C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)CCCCN)=O)C(C)C)=O)CCCNC(=N)N

• Molecular Formula :

  C49H94N16O9

• Molecular Weight :

  1051.37

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1413058-07-7