ER?17p

CAT: 0931-TP2682-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-TP2682-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
938077-77-1
Target
Apoptosis
Related Pathways
Apoptosis
Bioactivity
ER?17p (ER? 295-311), the epitope of the CaM binding site located on estrogen receptor ? (ER), interacts with calmodulin (CaM) in a calcium-dependent fashion. This peptide is involved in regulating the migration of various cancer cell lines including MCF-7, SK-BR-3, T47D, and MDA-MB-231 via the Rho/ROCK and PI3K/Akt signaling pathways. Additionally, ER?17p plays a role in suppressing proliferation and inducing apoptosis in breast cancer cells, as well as inhibiting tumor growth in mouse models.
Smiles
[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@@H](C)O)C(O)=O)=O)CC(C)C)=O)CO)=O)CC(C)C)=O)C)=O)CC(C)C)=O)CO)=O)CC(N)=O)=O)CCCCN)=O)CCCCN)=O)CO)=O)CCCNC(=N)N)=O)(NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@@H]1CCCN1)CC(C)C)=O)CCSC)=O)[C@H](CC)C)=O)CCCCN
Molecular Formula
C84H154N24O23S
Molecular Weight
1900.33
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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