ER-27319

CAT: 0931-T78641-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T78641-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

201010-95-9

Target

Syk

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis

Bioactivity

ER-27319, an acridone derivative, serves as a potent and selective inhibitor of spleen tyrosine kinase (SYK), effectively impeding both the tyrosine phosphorylation and enzymatic activity of SYK. With an inhibitory concentration (IC50) of 10 μM, this compound suppresses the release of allergic mediators from human and rat mast cells triggered by antigens, making it useful for allergy research [1] [2].

Smiles

C(C(O)=O)(O)=O.C(CCN)N1C=2C(C(=O)C=3C1=CC=CC3)=CC=C(C)C2C

Molecular Formula

C20H22N2O5

Molecular Weight

370.4

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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ER-27319

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