ER-27319

CAT: 0931-T78641-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T78641-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
201010-95-9
Target
Syk
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis
Bioactivity
ER-27319, an acridone derivative, serves as a potent and selective inhibitor of spleen tyrosine kinase (SYK), effectively impeding both the tyrosine phosphorylation and enzymatic activity of SYK. With an inhibitory concentration (IC50) of 10 µM, this compound suppresses the release of allergic mediators from human and rat mast cells triggered by antigens, making it useful for allergy research [1] [2].
Smiles
C(C(O)=O)(O)=O.C(CCN)N1C=2C(C(=O)C=3C1=CC=CC3)=CC=C(C)C2C
Molecular Formula
C20H22N2O5
Molecular Weight
370.4
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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