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SmMLCK peptide

CAT: 0931-TP2657-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP2657-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
172960-20-2
Target
Myosin
Related Pathways
Cytoskeletal Signaling
Bioactivity
The smMLCK peptide is a specific inhibitor of smooth muscle myosin light chain kinase (smMLCK) . It functions by mimicking the substrate and competitively inhibiting the binding of the natural substrate to the enzyme, thereby reducing kinase activity. This inhibition prevents the phosphorylation of the myosin light chain, which subsequently impedes muscle contraction.
Smiles
C([C@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)NC([C@H](C)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@@H](CC1=CN=CN1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CO)=O)CO)=O)CC(C)C)=O)CCCNC(=N)N)=O)=O)[C@H](CC)C)=O)C)=O)CCCNC(=N)N)=O)C(C)C)=O)C)=O)=O)=O)[C@@H](C)O)=O)CCCCN)=O)CCC(N)=O)=O)C=2C=3C(NC2)=CC=CC3
Molecular Formula
C98H168N38O25
Molecular Weight
2278.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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