JKC 301

• Target:

  Vasopressin Receptor

• Related Pathways:

  GPCR/G Protein

• Bioactivity:

  JKC 301, a selective Endothelin A receptor antagonist, attenuates the pressor effects of nicotine in rats and can be used to study cardiovascular disease caused by smoking [1] [2].

• Smiles:

  C(C=1C=2C(NC1)=CC=CC2)[C@@H]3C(=O)N[C@H](CC(O)=O)C(=O)N4[C@](C(=O)N[C@]([C@@H](CC)C)(C(=O)N[C@@H](CC(C)C)C(=O)N3)[H])(CCC4)[H]

• Molecular Formula:

  C32H44N6O7

• Molecular Weight:

  624.73

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  136553-96-3