QWF acetate

CAT: 0931-TP1946L-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-TP1946L-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Neurokinin receptor
Related Pathways
GPCR/G Protein|||Neuroscience
Purity
0.9665
Bioactivity
QWF acetate is a Substance P antagonist that specifically inhibits the binding of Substance P to its receptor (NK1) with an IC50 of 0.09 ?m; it can also inhibit the activation of Mas-related G-protein-coupled receptor X2 (MRGPRX2), which inhibits degranulation of mast cells.QWF acetate is used as a polypeptide in pain, inflammation and allergic reactions, QWF acetate has important applications as a peptide in the study of pain, inflammation and allergic reactions.
Smiles
O=C(OCC1=CC=CC=C1)[C@H](CC2=CC=CC=C2)NC([C@H](NC([C@H](CCC(N)=O)NC(OC(C)(C)C)=O)=O)CC3=CN(C=O)C4=CC=CC=C34)=O.OC(C)=O
Molecular Formula
C40H47N5O10
Molecular Weight
757.84
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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