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Dactinomycin

CAT: 0931-TN9827-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-TN9827-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
50-76-0
Target
DNA/RNA Synthesis|||Autophagy|||Apoptosis|||Antibacterial|||Antibiotic
Related Pathways
Microbiology/Virology|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Apoptosis|||Autophagy
Purity
0.997
Bioactivity
Dactinomycin D (Actinomycin IV) is an antibiotic and autophagy activator produced by Streptomyces bacteria fermentation, which inhibits transcription and replication by inserting into the DNA double helix, and can also promote p53 phosphorylation and accumulation through MDM2 overexpression, serving as a chemotherapy drug for cancer treatment.
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C(N[C@@H]1C(=O)N[C@H](C(C)C)C(=O)N2[C@@](CCC2)(C(=O)N(C)CC(=O)N(C)[C@@H]([C@@H](C)C)C(=O)O[C@@H]1C)[H])(=O)C=3C=4C(OC=5C(N4)=C(C(N[C@@H]6C(=O)N[C@H](C(C)C)C(=O)N7[C@@](CCC7)(C(=O)N(C)CC(=O)N(C)[C@@H]([C@H](C)C)C(=O)O[C@@H]6C)[H])=O)C=CC5C)=C(C)C(=O)C3N
Molecular Formula
C62H86N12O16
Molecular Weight
1255.42
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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100220Dactinomycin
S8964-50mgActinomycin D (Dactinomycin)
MBS651300-01Actinomycin D (Streptomyces antibioticus, Dactinomycin, Actinomycin IV, Actinomycin C1)

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