Actinomycin D (Dactinomycin)

CAT: 1568-C13823-01Size: 10 mgDry Ice: NoHazardous: No
C13823-0110 mg
Selected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
50-76-0
Synonyms
Act D, RASP-101
SKU
C13823-10mg
Target
DNA/RNA Synthesis
Applications
Cell Cycle
Molecular Formula
C62H86N12O16
Additionnal Information
Actinomycin D (Dactinomycin, Act D, RASP-101) is a significant polypeptide antibiotic isolated from soil bacteria of the genus Streptomyces. Actinomycin D (Dactinomycin) inhibits DNA repair and rests the cell cycle at G1 phase with IC50 of 0.42 μM and 0.4 nM, respectively. Actinomycin D is an autophagy activator, induces p53-independent cell death and prolongs survival in high-risk chronic lymphocytic leukemia.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive) . Please use it while wearing a protective face mask, gloves, and clothing.