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Pellotine

CAT: 0931-TN9164-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TN9164-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
19622-05-0
Target
5-HT Receptor
Related Pathways
GPCR/G Protein, Neuroscience
Bioactivity
Pellotine is an alkaloid isolated from Lophophora. It acts as an inverse agonist of the 5-HT7 receptor (5-HT7 receptor), with an EC50 of 291 nM. Pellotine shows strong affinity for the 5-HT1DR and 5-HT6R, with Ki values of 117 nM and 170 nM, respectively. Additionally, Pellotine reduces intracellular cAMP levels, thereby decreasing neuronal excitability and neurotransmitter release.
Smiles
OC=1C(OC)=C(OC)C=C2C1C(N(C)CC2)C
Molecular Formula
C13H19NO3
Molecular Weight
237.295
Shipping Conditions
Ice Packs
Storage Temperature
-20°C