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Nocarnickelamides B

CAT: 0931-TN9153-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TN9153-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Myosin, ROCK
Related Pathways
Cytoskeletal Signaling, Stem Cells, Cell Cycle/Checkpoint
Bioactivity
Nocarnickelamides B (Compound 2) is a linear peptide and an inhibitor of ROCK1/2. It exhibits dual inhibitory activity against ROCK1 and ROCK2, with IC50 values of 14.9 μM and 21.9 μM, respectively. This compound binds to the ATP binding site and inhibits ROCK-mediated cytoskeletal contraction markers, such as myosin light chain activation. Nocarnickelamides B can be utilized in glaucoma research.
Smiles
CCCCCc1ccccc1
Molecular Formula
C11H16
Molecular Weight
148.249
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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GTR19248374-01Nocarnickelamides B

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