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Avenanthramide C

CAT: 0931-TN8322-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-TN8322-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
116764-15-9
Target
AMPK|||IL Receptor|||Bcl-2 Family|||Caspase|||Interleukin|||TNF|||Adrenergic Receptor
Related Pathways
GPCR/G Protein|||PI3K/Akt/mTOR signaling|||Apoptosis|||Neuroscience|||Proteases/Proteasome|||Immunology/Inflammation|||Chromatin/Epigenetic
Purity
0.994
Bioactivity
Avenanthramide C is an orally available natural alkaloid with antioxidant/inflammatory properties that reduces the expression of TNF-a, BAK, IL-1b, and Bcl-2; reverses memory and behavioral deficits in Alzheimer's disease, with a reduction in caspase-3 cleavage and an increase in levels of pS9GSK-3? and IL-10, is able to bind ?1A adrenergic and stimulate AMPK; can attenuate noise and drug-induced hearing loss.
Smiles
N(C(/C=C/C1=CC(O)=C(O)C=C1)=O)C2=C(C(O)=O)C=C(O)C=C2
Molecular Formula
C16H13NO6
Molecular Weight
315.28
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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