Products for Research Use Only
RegisterLogin

Stellettin B

CAT: 0931-TN8158-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-TN8158-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
184885-91-4
Target
FAK, mTOR, PI3K, Autophagy, Apoptosis, Akt
Related Pathways
Apoptosis, PI3K/Akt/mTOR signaling, Angiogenesis, Cytoskeletal Signaling, Autophagy, Tyrosine Kinase/Adaptors
Bioactivity
Stellettin B, a triterpene compound isolated from the marine sponge Jaspis stellifera, has demonstrated notable anticancer properties. It induces G1 phase arrest, apoptosis, and autophagy in human non-small cell lung cancer A549 cells by inhibiting the PI3K/Akt/mTOR pathway. Additionally, Stellettin B reduces migration and invasion in hepatocellular carcinoma cells through the suppression of the MAPK and FAK/PI3K/AKT/mTOR signaling pathways. This compound is utilized in various cancer research studies.
Smiles
C[C@@]1\2[C@]([C@]3(C)[C@@](CC1)(C(C)(C)C(=O)CC3)[H])(CC(=O)/C2=C(\C=C\C=C(/C)\C=4OC(=O)C(C)=CC4)/C)[H]
Molecular Formula
C30H38O4
Molecular Weight
462.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T125695-01Stelletin A
T37756-01Phloxine B
T125095-01Monocillinol B
T124005-01Gingerglycolipid B
T34326-01Ridaifen-B
T124328-01Sibiriquinone B
T124366-01Psilostachyin B
T124518-01Senampeline B
T123912-01Rishirilide B
T124162-01Ginnalin B

Alternative Products

CatalogName
HY-N13176Stellettin B

Popular Products