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Microcolin H

CAT: 0931-TN7731-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-TN7731-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2408008-21-7
Target
ATG|||Autophagy|||p62
Related Pathways
Autophagy
Bioactivity
Microcolin H, a marine lipopeptide and phosphatidylinositol transfer protein ligand, targets PITP?/?. It enhances the conversion of LC3I to LC3II and decreases p62 levels in cancer cells, inducing autophagy cell death (Autophagy) . Furthermore, Microcolin H effectively inhibits tumor growth and exhibits anti-proliferative activity in nude mouse subcutaneous tumor models [1].
Smiles
C(=O)([C@H]1N(C([C@@H](N(C([C@@H](NC([C@@H](N(C([C@@H](CCCCCC)C)=O)C)CC(C)C)=O)[C@H](OC(C)=O)C)=O)C)[C@@H](C)C)=O)C[C@@H](O)C1)N2[C@@H](C)C=CC2=O
Molecular Formula
C38H63N5O9
Molecular Weight
733.93
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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